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Caryophyllene oxide is a sesquiterpene that results from the oxidation of β-caryophyllene, which can occur during the harvest's cure. ... Caryophyllene oxide is present in plants' profiles like eucalyptus, lemon balm, oregano, wormwood, rosemary, guava, black pepper, and clove.
It's also present in many spices like basil, black pepper, and oregano, among other cannabis strains. It delivers a spicy, woody, funky warmth similar to cinnamon and cloves aroma. It has been used in cosmetics, drugs, food preservatives, and for training drug-sniffing dogs by law enforcement.